Tsubo Lab イノベーションで、世界をごきげんに、健康にする

Through innovation in health and medical fields,
we will make the world happier and healthier.

  • 近視
  • ドライアイ
  • 老眼






Tsubota Laboratory, a startup from Keio University, develops innovative solutions for myopia, dry eyes and presbyopia.

Through innovation in health and medical fields, we will make the world happier and healthier.
We will expand the possibility of our partner companies by revolutionary medicine, supplements, medical devices and health products that are developed based on science.


Development of Innovative Treatment for Dry Eye

Based on the knowledge of our Founding Scientist, Prof. Kazuo Tsubota, we are working on the development of innovative treatment, prevention and medical devices on dry eyes. An evidence-based dietary supplement for prevention and also simple diagnostic tools have been developed. Our challenges continue to develop a patent-pending novel medical device to moisten  the eyes.

Related Papers

Myopia Prevention for Kids!

To stop the global increase of myopia, we are doing research on a novel violet light theory. Our dream is to protect children from myopia through our new myopia prevention method and clinical applications. Besides medical approaches, we believe there exist factors in our lifestyle to worsen myopia, for which we will offer evidence based solutions. Myopia is a risk factor for blindness. Our hope is to protect kids from myopia and offer the healthy vision life.

Related Papers

Innovative Solutions for Presbyopia

Presbyopia can be considered as a sign of aging, not only in eyes but the entire body. It has been thought inevitable under the aging process, and the most common solution that clinicians provide is still “reading glasses”. We are developing anti-oxidant supplement for prevention, as well as measurement techniques for the stiffness of crystalline lens.

Related Papers


Tsubota Laboratory, Inc.
February 19th 2015
Paid-in Capital:
201,553,000 yen
Founding Scientist・
Kazuo Tsubota
304 Toshin Shinanomachi-ekimae Bldg.,
34 Shinanomachi Shinjuku-ku,
Tokyo 160-0016, JAPAN

Please check Tsubota Lab Update Report 2020!


坪田一男 / Kazuo Tsubota
坪田一男 / Kazuo Tsubota
Professor Emeritus in Department of Ophthalmology, Keio University School of Medicine
  • ごあいさつ:
  • 坪田ラボは、加速する高齢化やデジタル社会を背景に激増しているドライアイ、近視、老眼の3つの領域で
  • イノベーションを起こし、サイエンスに基づいた革新的なアプローチで健康と快適を人々に届けることをミッションとしています。
  • パートナー企業とともに成長し、社会に貢献できるように、そして慶應大学発ベンチャーの規範となるべく
  • 切磋琢磨してまいります。
  • Biography:
  • 慶應義塾大学医学部卒業。
  • ハーバート大学角膜クリニカルフェロー修了。世界に先駆けた、角膜上皮の幹細胞移植による再生治療の実績で注目を集めた。
  • また、ドライアイにいち早く着目し、数多くの論文を発表。
  • 角膜移植の分野では、日本のアイバンクにアメリカ式のシステムを導入し新しい医療を展開。
  • 日本抗加齢医学会理事長(2013年6月~2017年6月)現理事、ドライアイ研究会Founding President、近視研究会世話人代表などの要職を務める。
  • Kazuo Tsubota, MD
  • Professor Emeritus of Department of Ophthalmology,
  • Keio University School of Medicine
  • World’s most prolific researcher in the dry eye field
  • World’s first corneal epithelial stem-cell transplantation
  • President of Myopia Society Japan
  • Former President of Japanese Society of Anti-Aging Medicine
  • President of Vision Healthcare Foundation
  • Chief editor of “npj-Aging and Mechanisms of Disease” magazine
  • Currently in the Executive MBA course of Keio Business School

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